You don’t have to be an expert landscaper to know that there are absolutely no reasons to ever have weeds on your property. Weeds are ugly, invasive, and sometimes even dangerous to an extent. If you have weeds, you want them gone. Period. We can all agree on that. Â
So how do you get rid of weeds? Unless you want to spend all your time pulling them all out by hand, weed killers are the only logical solution.
Anyone that has a property with vegetation knows the struggles and problems weeds can cause, whether you have a front and backyard, a garden, or are trying to keep your landscaping at its best for a commercial property. That’s where weed killers come in.
Overall Best Weed Killer: Compare and Save Weed Killer
You shouldn’t compromise on any options when you have the best. Compare N Save stays true to its name of saving your grass from weed. It has got it all, right from being rainproof to be able to see the results in just 2-4 days.
Top 15 Best Weed Killers of 2025
| Â Â Name | Main Ingredient | Size | Â |
|---|---|---|---|
| Â Â Compare and Save | Glyphosate | 1 Gal | Buy Now |
| PBI/Gordon 652400 Speed Zone | Glyphosate | 1/2 Gal | Buy Now |
| Â Â Roundup 5200210 | Glyphosate + Pelargonic Acid | 1.3 Gal | Buy Now |
| Â Â Roundup Extended II | Glyphosate + Imazapic | 1 Gal | Buy Now |
| Â Â Ortho GroundClear | Glyphosate + Imazapyr | 2 Gal | Buy Now |
| Â Â Bayer Crop Science | Glyphosate + Diquat Dibromide and Indaziflam | 4 Gal | Buy Now |
| Â Â Fertilome 33692 | Glyphosate | 0.25 Gal | Buy Now |
| Â Â Spectracide | Glyphosate + Diquat Dibromide | 1 Gal | Buy Now |
| Â Â Bonide Burnout | Citric acid and Clove oil | 1 Gal | Buy Now |
| Â Â Preen Garden | Trifluralin | – | Buy Now |
| Â Â Southern Ag | 2, 4 D | – | Buy Now |
| Â Â Fertilome Weed Killer | 2, 4 D | 0.25 Gal | Buy Now |
| Â Â Ortho Weed-B-Gon | 2, 4 D | 0.31 Gal | Buy Now |
| Â Â Hi-Yield | 2, 4 D | – | Buy Now |
| Â Â Southern Ag Crossbow Specialty | 2, 4 D | 0.25 Gal | Buy Now |
Our #1 Recommendation: Best Overall
Compare and Save weed killer is one of the most popular you’ll find, and for very good reason. It’s affordable, incredibly efficient, and you get a lot of it with one order. Add it all up, and you have our pick for the best conventional weed killer on the market.
This product is non-selective, so you will need to target it directly on the growths you want removed, as it will kill whatever it touches. Glyphosate is the main active ingredient, which accounts for 41% of the concentrate.
This particular size is one gallon, which can be mixed to cover up to 300 square feet.
Depending on your weed amount, it could very well treat even more space. Seeds are safe to plant 24 hours after treating the area.
Mixing is fairly standard. Take 1.5 ounces of concentrate and mix it with 1 gallon of water for general weed control. Tougher weed control of perennials or brush will require a mix of 2.5 ounces in 1 gallon of water.
It’s worth mentioning that this product is very potent, and can take it whatever you spray it on, so it has an astounding amount of versatility. You can definitely kill any vegetation you don’t want around, which of course includes grass making it one of the best permanent vegetation killers.
Compare-N-Save’s Concentrate Grass and Best Weed Killers is as economical as it is effective. If you’re okay to use non-selective herbicides, and you want an affordable product that can treat a large area, this is the one of the best herbicides to buy.
Our #2 Recommendation : Best Budget
The PBI/Gordon 652400 is an excellent choice if weeds such as wild violets and crabgrass have been wreaking havoc in your lawn. It’s a powerful herbicide that does quick work of any pesky grass or weed; either the weeds die or at least enter a state where they can no longer recover. In particular, this works wonders against dandelions.
You may think this is only good if you have a big lawn. However, the PBI/Gordon 652400 is just as useful in regular-sized properties. For one, you can just spray individual weeds instead of targeting entire sections of the lawn. You’ll see how effective the herbicide is as the weeds begin to fall down in more or less 12 hours.Â
Of course, you must practice care when you apply this weed killer. The PBI/Gordon 652400 can still kill off your desirable grasses if you spray a considerable amount onto them. But if you do things right, you can sow fresh seeds in the weeded area in a mere two weeks.Â
The manufacturer does not ship the product to five states, so take note of your location. Other than this, the PBI/Gordon 65400 is an impressive lawn weed killers who wants quick and consistent results.
More Great Buys
Roundup 5200210:Â Best Weed and Grass Killer
If Roundup’s other products aren’t getting the job done for you, or if you’re simply looking for one that you don’t have to mix yourself into a sprayer, but still want proven weed-killing ability from a reliable manufacturer, Weed and Grass Killer III is worthy of your consideration.
Weed and Grass Killer III combines the ever-popular glyphosate with another strong active ingredient; pelargonic acid. This gives the product a very efficient one-two punch that will take out basically anything it comes in contact with, right down to the root.
Roundup Extended II Concentrate:Â Best Preventative + WeedKiller
Sometimes you need a weed killer that not only kills weeds, but keeps new ones from sprouting up right afterwards. Roundup’s Extended Weed Control and Grass Killer Plus Weed Preventer II does exactly that, combining a potent weed and grass killer with preventative measures that will keep the area clearer for longer.
Like most others, Extended Weed Control and Grass Killer Plus Weed Preventer II uses glyphosate as its main active ingredient, but also contains a small amount of imazapic, which helps prevent new weeds from growing for months after use.
This particular size is 16 ounces, which is less than the half and one-gallon sizes that make up most of this list, but that’s by design.Â
Since this is a weed preventer as well, you won’t need to be using as much as you would with a normal one, as the preventer ensures less applications.
6 ounces of Extended Weed Control and Grass Killer Plus Weed Preventer II can be mixed with one gallon of water or standard use. A pump sprayer is best, and this product can then be applied to numerous areas, including gravel, mulch, tree rings, fence lines, and much more.
For those who want to limit their applications, Roundup Extended Weed Control and Grass Killer Plus Weed Preventer II is the most effective weed killer for lawns . You get Roundup’s winning weedkiller mixture, combined with a proven weed preventer that will keep the applied area free of unwanted growths for up to 4 months. That’s as good as it gets making it one of the best lawn weed killers.
Ortho GroundClear Vegetation Killer Concentrate: Top Rated Weed Killer + Preventative
Ortho Groundclear does exactly was the name describes. Weeds, grass, plants — all of these are no match for its potent chemical blend. And better yet, it keeps these weeds and other vegetation away for a very, very long time making it one of the best vegetation killers available in market.
Groundclear uses glyphosate as its base, and adds in imazapyr as a secondary ingredient to prevent new growth. You still get fast-acting results you’ll see in just a few hours, while also withstanding rain after 30 minutes of settling.
This is a concentrate in every way.
You have the option to use whichever ratio you’d like, but even a few ounces in a gallon of water will give you enough potency to effectively treat a large area. This is two gallons, so it’s definitely going to last you awhile.
After application, you’ll see weeds, grass, and other plants that have been sprayed start withering away after a few hours. The effect will last up to one full year after you spray it, which is far longer than most other weed killer + preventers on the market. This makes Groundclear very good for larger yards.
Don’t be deceived by the higher price. With Ortho’s Groundclear, you’re not only getting two full gallons of concentrate, you’re getting a product that will annihilate anything it touches, and keep it from coming back for nearly a year.
Bayer Crop Science 704330A:Â Good Weed Killer + Preventative
Bayer’s Advanced Durazone Concentrate is dual-action weed killer that can quickly eliminate weeds and other bothersome vegetation in a matter of hours, while also preventing new growth for up to 6 full months.
Durazone WeedKiller uses glyphosate as its main ingredient, and backs it up with a combination of diquat dibromide and indaziflam, giving it a three-way attack that easily kills all the way down to the root.
This economical 32 ounce size can be used to make 4 full gallons of usable herbicide, which is best applied when using a pump sprayer.
You can get about 1,500 square feet of use out of just one bottle, making it great for larger landscapes and yards.
Any area where you apply Durazone Concentrate will stay clear for 6 months, so you can quickly kill weeds and control them using the same product, while cutting down on the number of times you’ll need to use it. This product is most effective on driveways, sidewalks, mulched areas, and along fences as well.
Bayer Advanced Durazone is among the best you can use for weed killers that also prevent new growths for an extended amount of time. The low price and expanded area range makes it one of the best weed control concentrates for anyone needing to be rid of and control weeds.
Fertilome is a lesser-known manufacturer, which is a shame since they make one of the most effective and affordable weed killers you can find. Killzall Weed and Grass Killer lives up to its name, as it wipes out whatever you spray it on.
Killzall Weed and Grass Killer uses a large amount of glyphosate as its main ingredient and nothing else, relying on the power of this widely-used vegetation killer.
You get 32 ounces with this purchase, and although it’s not as much as some other products, the ratio for mixing is quite lower.Â
You can use just 5 tablespoons of Killzall Weed and Grass Killer to treat a gallon of water, and that’s enough to kill even the toughest of weeds.
Killzall Weed and Grass Killer can be used anywhere that you have unwanted weeds and grass, but be aware that it will kill any vegetation it ends up on, so don’t use it around fruit and veggie gardens. It is rainproof after sitting for two full hours.
Fertilome Killzall Weed and Grass Killer may not be flashy, but it gets the job done, and it’s available for an extremely low price under $10. If you want to kill as many weeds as possible while spending the least amount of money, this is the way to do it.
Spectracide Weed and Grass Killer 2 is one of the most economical weed killers on this list, and it performs on the same level as similar products that cost twice as much. As a general weed and grass killer this is hard to beat, especially when considering the price.
Weed and Grass Killer 2 forgoes the usual glyphosate for a mix of active ingredients that is anchored by diquat dibromide, and supported with an array of other effective killers. This combination results in one of the most fact-acting products you’ll encounter.
Weed and Grass Killer 2 comes in a one gallon size, and includes its own sprayer, so you can use it as soon as it arrives. While not a concentrate, it does not require much of a spray to be effective. The product has no soil activity, so it won’t affect nearby untreated plants.
You can use this killer anywhere you’d use similar products, which includes walkways, mulch, tree rings, fence lines, and of course cement cracks in a sidewalk, patio, or driveway. You’ll see results in about 3 hours, and the product is rainproof after sitting for 15 minutes.
Spectracide Weed and Grass Killer 2 is best for those who haven’t had a lot of good results with glyphosate, and need to kill weeds such as dandelions, plantains, and blue grass, while saving as much money as possible. Considering the price it is one of the best commercial weed killers in the market.
For those that take an organic approach to their gardening, or simply want to avoid the use of chemicals, Bonide’s Burnout Natural is an excellent choice. Intended mostly for grassy and broadleaf weeds, this product is surprisingly effective when used properly.
The active ingredients in Bonide Burnout are citric acid and clove oil, which not only avoids spraying chemicals on your yard, they actually pleasant to smell as well. Yes, you’ll need to spray more onto the weed than you would with chemical products, but it works, and it works well.
This size of Bonide’s Burnout is one gallon, and it is not a concentrate. Still, when considering the price, it’s a great value, especially since it comes with an integrated sprayer, saving you from having to buy a seperate one and/or also mixing with water.
Although this product is made to kill weeds, it can also be used to remove stubborn grass growth in cement cracks, and as a spot treatment within your garden for wayward weeds and unwanted grass growth.
Natural weed killers sometimes get a bad rap, mainly because they aren’t as potent as chemical weed killers. That’s not the case with Bonide’s Burnout Natural, as it’s effective when used correctly, and safe to use around people, pets, and other things you may be growing. Definitely a great product.
Scotts is a huge brand when it comes to lawn products, but it seems it’s made a slight misstep with this weed preventer. This is specifically made to stop crabgrass weed from growing in your lawn throughout the season. It’s true that it works with just one application, but there is definitely room for improvement.
For one, the Scotts Halts Weed Preventer results in a lot of stains. If you use it with your bare hands, prepare to wash your hands thoroughly afterward. You should also wear clothes you don’t mind getting dirty. Simply put, this weed preventer isn’t exactly the tidiest way to stop crabgrass from spreading.
Second, the packaging isn’t ideal. The Scotts Halts Weed Preventer comes in two packs — the problem is that the products aren’t all fixed in one area. If you don’t want any mess, you should unpack the product with the utmost care. On the flip side, this is a weed preventer that you can use in spring and fall.
If you use it during fall, you may notice that winter weeds aren’t as prominent. It’s a bonus that the Scotts Halts Weed Preventer keeps moss away as well. So if you don’t mind the stains, you should consider this lawn product — especially since neither rain nor snow will ruin its efficiency.
A favorite among landscapers for years, Southern Ag’s 2, 4 D Amine Weed Killer contains a very potent blend of herbicides specifically designed to take out all the things you don’t want, while leaving your grass fully intact — even St. Augustine grass.
This product uses a 46.3% ratio of 2, 4 D, which makes it easy to stretch this one quart container into acres and acres of usage, especially when applied selectively rather than broadly.
In about 7 days, leafy broadleaf weeds will begin to die off, while your grass and other vegetation will thrive.
This makes it ideal for use on golf courses, along fences and ditches, industrial sites, and of course your front and back yards.
Do keep in mind that this is a container with concentrate only, so you’ll need to provide your own mixing, and a means in which to spray the herbicide.
For just over $20, it’s hard to think of a more effective 2, 4 D weed killer for such an economical price. You get both value and results with Southern Ag’s 2, 4 D Amine Weed Killer, and I highly recommend it.
Fertilome’s Weed Killer is another excellent selective herbicide that achieves quick and sustained results, while boasting an ideal chemical ratio that allows it to target a variety of unwanted growths in and around your property.
This product uses 2,4 D at a ratio of 10.49% with small amounts of Mecoprop-p and Dicamba giving it a little more versatility than usual. Just 4 ounces of the weed killer can create 2 full gallons of herbicide.
Fertilome Weed Killer comes in a 32 ounce size, and is especially effective for clover, ground ivy, cottonwood, spurge, and
chickweed, but will definitely take care of most any broadleaf weed, while of course leaving your grass in perfect condition with proper use.
Application is best done in dry conditions, and before the weather starts to get above 85 degrees Fahrenheit.
Fertilome Weed Killer is a bit more expensive than other products, but its potent and targeted mix of herbicides makes it one of the most effective selective weed killers you’ll ever use.
For those looking for a product that goes beyond just the typical weed control, Ortho Weed-B-Gon Plus Crabgrass Control is a worthy purchase that works in more ways than one
This product obviously uses 2, 4 D, but also has additional chemicals that specifically target unwanted crabgrass that can threaten to overtake your yard. And just like its selectie nature, you can apply to any areas with weeds and crabgrass, but without killing and of your normal grass.
The weed killer has been pre-mixed, so there’s no need to worry about doing it yourself.Â
This particular version comes with a crabgrass wand, making application even easier and more seamless.
40 ounces is a lot less than you get with a concentrate, but if you are using this on a standard sized lawn, it’s enough to go around. A one gallon version is available for those with larger yards or property needs.
The combination of crabgrass and weeds are common threats to many yards. Ortho Weed-B-Gon Plus Crabgrass Control offers an all-in-one solution for a fair price, which is why I recommend it.
Looking for the most bang for your buck? Hi-Yield 2, 4 D Selective Weed Killer provides buyers with a large amount of concentrate for little money, while also providing big results against practically every kind of weed.
This agriculture-grade, one gallon jug has a ratio of over 11%, and can easily make 4 to 5 gallons of usable herbicide. It’s perfect for large properties, along ditches and fences, and really anywhere else you’d like to control weeds on a long term basis.
Plantains, chickweed, dandelion, and even poison ivy are all susceptible to this herbicide, and since it’s 2, 4 D, your grass won’t suffer a bit.
For just over $25, you won’t find a more powerful and plentiful selective weed killer. It may not be a major brand, but Hi-Yield products have been a secret favorite among landscapers and acreages homeowners for years. Use it and you’ll see why.
Another Southern Ag weed killer makes the list, this time as a unique mix of both 2, 4 D and triclopyr together in one product. Crossbow Specialty Herbicide is a powerful and versatile weed killer that can easily take down both brush, weeds, and even small trees taking over your grass.
The combination of 2, 4 D and triclopyr have been delicately balanced for maximum efficacy, while still protecting your grass areas. If you have a large lot that hasn’t received attention for a while, or just have a large amount of sudden unwanted growth, this product can handle it all ith ease.
And while this may be just a 32 ounce bottle, all it takes is 1 and ⅓ ounce per gallon, so you’re getting over 25 gallons of herbicide from one bottle, and all for under $30.
If you need a little more boost to standard 2, 4 D weed killers, Southern Ag’s Crossbow will certainly get the job done.
What is the Best Weed Control that You Should Buy ?
Breaking down the different types and uses of weed killers is quite simple when you base it off of what they are capable of.
This is the most basic form of these products. If the weed killer is simply marketed as a weedkiller and nothing more, it’s safe to assume that it will kill weeds and other vegetation on contact, but it’s up to you on how to prevent new growth in the future — or just apply again as needed.
Great For:Â Killing weeds and grass in small areas, such as sidewalks, driveways, walking paths, and spot treatment in smaller mulched areas and tree rings.
Weed Killer + Controllers will not only kill the weeds, but prevent new ones from forming on that same spot. They usually have one ingredient for killing the weed, and another that penetrates the soil and prevents anything else from growing.
Great For:Â High volume weed areas away from desirable vegetation, tree rings, larger sidewalks and driveways.
Weed preventative products aren’t technically weed killers in the fullest sense, but they are still closely related. These are often granular spreads that you can use like fertilizer, but only work where there aren’t any weeds.
Weed preventatives are most effective when they follow up weed killers after a few weeks, or after you’ve removed weeds in the treated area by hand.
Great For:Â Gardens, planters, mulched flower beds.
Not everyone likes to use chemicals on their property, be it for ecological reasons, or protect wildlife and edible vegetation these are one of the best weed killers that you can buy.
Natural and/or organic killers often use concentrated oils derived from any number of organic compounds, including citrus, mint, and clove. These can be just as effective as conventional weed killers when used on the right weeds and vegetation. You can make your own weed killer by simply following the steps given in this post by Naturallivingideas.com
Great For:Â The environmentally conscious, food and herb gardens, those with visiting wildlife, pets, and small children.
Before You Buy
The most important thing you need to determine before actually purchasing a weed killer is the type of weed(s) you are dealing with. Identifying the type of weed will allow you to choose the right product that specifically targets that weed, leading to more effective results, while also protecting your other plants and grass.
Do you know what type of weed is it? If not, take a close look at this handy weed identification guide for help.
Do you want to kill the weeds only, or everything including your grass?
Certain types of weed killers react differently to other types of vegetation. You can take the all-out approach of using a weed killer that kills everything it touches, or use more selective
products that either target just weeds, or weeds and other brush-like vegetation.
This is the core difference between selective and non-selective weed killers.
- Selective weed killers only kill the weed, and leave grass unaffected.
- Non-selective weed killer kills anything it touches, be it weeds, grass, or other vegetation.
The advantages a car air freshener provides should be fairly obvious. Depending on which one you get, you can restore that long gone new car smell, mask unpleasant smells, or simply add your own personal scent choice to the interior, helping improve the feel and environment when inside.
Triclopyr is a popular herbicide that kills both weeds and brush, but it can be more expensive for the most part.
On the other hand, 2, 4 D weed killers are popular due to their more specific targeting of weeds that leaves grass unaffected. The compound in 2, 4 D products causes weeds to grow at an abnormal rate for a week or two, causing them to die off.
2, 4 D makes it easy to apply throughout a yard, without worrying about accidentally killing your grass. This makes it ideal for yards with spotty weed occurrences randomly throughout.
